USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P49792 USC-OGP 2-DE database:  P49792 P49792 General information about the entry View entry in simple text format Entry name RBP2_HUMAN Primary accession number P49792 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=E3 SUMO-protein ligase RanBP2; EC=6.3.2.-; AltName: Full=358 kDa nucleoporin; AltName: Full=Nuclear pore complex protein Nup358; AltName: Full=Nucleoporin Nup358; AltName: Full=Ran-binding protein 2; Short=RanBP2; AltName: Full=p270;. Gene name Name=RANBP2 Synonyms=NUP358 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0301: pI=5.85; Mw=74882 Cross-references UniProtKB/Swiss-Prot P49792; RBP2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name RBP2_HUMAN Primary accession number P49792 Secondary accession number(s) Q13074 Q15280 Q53TE2 Q59FH7 Sequence was last modified on  December 6, 2005 (version 2) Annotations were last modified on  March 15, 2017 (version 195) Name and origin of the protein Description RecName: Full=E3 SUMO-protein ligase RanBP2; EC=6.3.2.-; AltName: Full=358 kDa nucleoporin; AltName: Full=Nuclear pore complex protein Nup358; AltName: Full=Nucleoporin Nup358; AltName: Full=Ran-binding protein 2; Short=RanBP2; AltName: Full=p270; Gene name Name=RANBP2 Synonyms=NUP358 Encoded on Name=RANBP2; Synonyms=NUP358 Keywords 3D-structure; Acetylation; Complete proteome; Disulfide bond; Isopeptide bond; Ligase; Membrane; Metal-binding; Methylation; mRNA transport; Nuclear pore complex; Nucleus; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; RNA-binding; TPR repeat; Translocation; Transport; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L41840; AAC41758.1; -; Genomic_DNA EMBL D42063; BAA07662.1; -; mRNA EMBL AC010095; AAY14984.1; -; Genomic_DNA EMBL AB209483; BAD92720.1; -; mRNA EMBL U19248; AAA85838.1; -; mRNA CCDS CCDS2079.1; -; . PIR S58884; S58884; . RefSeq NP_006258.3; NM_006267.4; . UniGene Hs.199561; -; . UniGene Hs.715056; -; . PDB 1RRP; X-ray; 2.96 A; B/D=1171-1304 PDB 1XKE; NMR; -; A=2028-2154 PDB 1Z5S; X-ray; 3.01 A; D=2631-2711 PDB 2LAS; NMR; -; B=2705-2717 PDB 3UIN; X-ray; 2.60 A; D=2629-2695 PDB 3UIO; X-ray; 2.60 A; D=2631-2695 PDB 3UIP; X-ray; 2.29 A; D=2631-2695 PDB 4GA0; X-ray; 1.15 A; A=1-145 PDB 4I9Y; X-ray; 1.75 A; A/B/C/D/E/F=3062-3224 PDB 4L6E; X-ray; 2.50 A; A=2907-3050 PDB 4LQW; X-ray; 1.95 A; A/B=3057-3224 PDB 5CLL; X-ray; 2.45 A; B/D=1155-1321 PDB 5CLQ; X-ray; 3.20 A; B/D=1155-1321 PDBsum 1RRP; -; . PDBsum 1XKE; -; . PDBsum 1Z5S; -; . PDBsum 2LAS; -; . PDBsum 3UIN; -; . PDBsum 3UIO; -; . PDBsum 3UIP; -; . PDBsum 4GA0; -; . PDBsum 4I9Y; -; . PDBsum 4L6E; -; . PDBsum 4LQW; -; . PDBsum 5CLL; -; . PDBsum 5CLQ; -; . ProteinModelPortal P49792; -; . SMR P49792; -; . BioGrid 111839; 147; . DIP DIP-37654N; -; . IntAct P49792; 62; . MINT MINT-191403; -; . STRING 9606.ENSP00000283195; -; . TCDB 1.I.1.1.3; the nuclear pore complex (npc) family; . iPTMnet P49792; -; . PhosphoSitePlus P49792; -; . SwissPalm P49792; -; . BioMuta RANBP2; -; . DMDM 83305554; -; . OGP P49792; -; . EPD P49792; -; . MaxQB P49792; -; . PaxDb P49792; -; . PeptideAtlas P49792; -; . PRIDE P49792; -; . Ensembl ENST00000283195; ENSP00000283195; ENSG00000153201; . GeneID 5903; -; . KEGG hsa:5903; -; . UCSC uc002tem.4; human; . CTD 5903; -; . DisGeNET 5903; -; . GeneCards RANBP2; -; . H-InvDB HIX0002358; -; . HGNC HGNC:9848; RANBP2; . HPA CAB034063; -; . HPA HPA018437; -; . HPA HPA023960; -; . HPA HPA049497; -; . HPA HPA051675; -; . HPA HPA067564; -; . MalaCards RANBP2; -; . MIM 601181; gene; . MIM 608033; phenotype; . neXtProt NX_P49792; -; . OpenTargets ENSG00000153201; -; . Orphanet 263524; Acute necrotizing encephalopathy of childhood; . Orphanet 88619; Familial acute necrotizing encephalopathy; . Orphanet 178342; Inflammatory myofibroblastic tumor; . PharmGKB PA34209; -; . eggNOG KOG0864; Eukaryota; . eggNOG KOG0865; Eukaryota; . eggNOG COG0652; LUCA; . eggNOG COG5171; LUCA; . GeneTree ENSGT00760000119119; -; . HOGENOM HOG000089994; -; . HOVERGEN HBG092361; -; . InParanoid P49792; -; . KO K12172; -; . OMA PGKQNQT; -; . OrthoDB EOG091G0BGL; -; . PhylomeDB P49792; -; . TreeFam TF314797; -; . Reactome R-HSA-1169408; ISG15 antiviral mechanism; . Reactome R-HSA-159227; Transport of the SLBP independent Mature mRNA; . Reactome R-HSA-159230; Transport of the SLBP Dependant Mature mRNA; . Reactome R-HSA-159231; Transport of Mature mRNA Derived from an Intronless Transcript; . Reactome R-HSA-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript; . Reactome R-HSA-165054; Rev-mediated nuclear export of HIV RNA; . Reactome R-HSA-168271; Transport of Ribonucleoproteins into the Host Nucleus; . Reactome R-HSA-168276; NS1 Mediated Effects on Host Pathways; . Reactome R-HSA-168325; Viral Messenger RNA Synthesis; . Reactome R-HSA-168333; NEP/NS2 Interacts with the Cellular Export Machinery; . Reactome R-HSA-170822; Regulation of Glucokinase by Glucokinase Regulatory Protein; . Reactome R-HSA-180746; Nuclear import of Rev protein; . Reactome R-HSA-180910; Vpr-mediated nuclear import of PICs; . Reactome R-HSA-191859; snRNP Assembly; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2500257; Resolution of Sister Chromatid Cohesion; . Reactome R-HSA-3108214; SUMOylation of DNA damage response and repair proteins; . Reactome R-HSA-3301854; Nuclear Pore Complex (NPC) Disassembly; . Reactome R-HSA-3371453; Regulation of HSF1-mediated heat shock response; . Reactome R-HSA-4570464; SUMOylation of RNA binding proteins; . Reactome R-HSA-4615885; SUMOylation of DNA replication proteins; . Reactome R-HSA-5578749; Transcriptional regulation by small RNAs; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-6784531; tRNA processing in the nucleus; . Reactome R-HSA-68877; Mitotic Prometaphase; . UniPathway UPA00886; -; . ChiTaRS RANBP2; human; . EvolutionaryTrace P49792; -; . GeneWiki RANBP2; -; . GenomeRNAi 5903; -; . PRO PR:P49792; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000153201; -; . CleanEx HS_RANBP2; -; . ExpressionAtlas P49792; baseline and differential; . Genevisible P49792; HS; . GO GO:0005642; C:annulate lamellae; IDA:UniProtKB; . GO GO:0005813; C:centrosome; IBA:GO_Central; . GO GO:0005737; C:cytoplasm; IBA:GO_Central; . GO GO:1990723; C:cytoplasmic periphery of the nuclear pore complex; IEA:Ensembl; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0005635; C:nuclear envelope; IDA:UniProtKB; . GO GO:0042405; C:nuclear inclusion body; IDA:UniProtKB; . GO GO:0031965; C:nuclear membrane; IDA:UniProtKB; . GO GO:0005643; C:nuclear pore; IDA:UniProtKB; . GO GO:0044614; C:nuclear pore cytoplasmic filaments; IDA:GO_Central; . GO GO:0044615; C:nuclear pore nuclear basket; IDA:UniProtKB; . GO GO:0016874; F:ligase activity; IEA:UniProtKB-KW; . GO GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro; . GO GO:0008536; F:Ran GTPase binding; IPI:GO_Central; . GO GO:0003723; F:RNA binding; IEA:UniProtKB-KW; . GO GO:0019789; F:SUMO transferase activity; EXP:Reactome; . GO GO:0008270; F:zinc ion binding; IEA:InterPro; . GO GO:0051642; P:centrosome localization; IMP:UniProtKB; . GO GO:0000082; P:G1/S transition of mitotic cell cycle; IBA:GO_Central; . GO GO:0031047; P:gene silencing by RNA; TAS:Reactome; . GO GO:0075733; P:intracellular transport of virus; TAS:Reactome; . GO GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome; . GO GO:0006406; P:mRNA export from nucleus; TAS:Reactome; . GO GO:0033132; P:negative regulation of glucokinase activity; IEA:Ensembl; . GO GO:0006607; P:NLS-bearing protein import into nucleus; IMP:GO_Central; . GO GO:0043547; P:positive regulation of GTPase activity; IEA:GOC; . GO GO:0046604; P:positive regulation of mitotic centrosome separation; IBA:GO_Central; . GO GO:0006457; P:protein folding; IEA:InterPro; . GO GO:0016925; P:protein sumoylation; IDA:UniProtKB; . GO GO:1900034; P:regulation of cellular response to heat; TAS:Reactome; . GO GO:0090526; P:regulation of gluconeogenesis involved in cellular glucose homeostasis; IEA:Ensembl; . GO GO:0010827; P:regulation of glucose transport; TAS:Reactome; . GO GO:0001975; P:response to amphetamine; IEA:Ensembl; . GO GO:0006405; P:RNA export from nucleus; IBA:GO_Central; . GO GO:0007062; P:sister chromatid cohesion; TAS:Reactome; . GO GO:0007051; P:spindle organization; IBA:GO_Central; . GO GO:0006409; P:tRNA export from nucleus; TAS:Reactome; . GO GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central; . GO GO:0016032; P:viral process; TAS:Reactome; . GO GO:0019083; P:viral transcription; TAS:Reactome; . Gene3D 1.25.40.10; -; 2; . Gene3D 2.30.29.30; -; 4; . Gene3D 2.40.100.10; -; 1; . InterPro IPR029000; Cyclophilin-like_dom; . InterPro IPR020892; Cyclophilin-type_PPIase_CS; . InterPro IPR002130; Cyclophilin-type_PPIase_dom; . InterPro IPR022011; IR1-M; . InterPro IPR011993; PH_dom-like; . InterPro IPR000156; Ran_bind_dom; . InterPro IPR013026; TPR-contain_dom; . InterPro IPR011990; TPR-like_helical_dom; . InterPro IPR019734; TPR_repeat; . InterPro IPR001876; Znf_RanBP2; . Pfam PF12185; IR1-M; 2; . Pfam PF00160; Pro_isomerase; 1; . Pfam PF00638; Ran_BP1; 4; . Pfam PF00641; zf-RanBP; 8; . PRINTS PR00153; CSAPPISMRASE; . SMART SM00160; RanBD; 4; . SMART SM00028; TPR; 1; . SMART SM00547; ZnF_RBZ; 8; . SUPFAM SSF48452; SSF48452; 1; . SUPFAM SSF50729; SSF50729; 4; . SUPFAM SSF50891; SSF50891; 1; . SUPFAM SSF90209; SSF90209; 7; . PROSITE PS00170; CSA_PPIASE_1; 1; . PROSITE PS50072; CSA_PPIASE_2; 1; . PROSITE PS50196; RANBD1; 4; . PROSITE PS50005; TPR; 1; . PROSITE PS50293; TPR_REGION; 1; . PROSITE PS01358; ZF_RANBP2_1; 8; . PROSITE PS50199; ZF_RANBP2_2; 8; .

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